I-cell disease - ggccjj

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Mistargeting of lysosomal enzymes, a problem identified in patients with mucolipidosis II (I-cell disease), involves a defect in which of the following mechanisms involving lysosomal proteins?

A. N-linked glycosylation
B. O-linked glycosylation
C. Phosphorylation of mannose residues
D. Protease responsible for conversion of precursor
E. Sialylation of N-linked oligosaccharides

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cc

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C. Phosphorylation of mannose residues

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C.

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Pjosphorulation of mannose..C

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CCCCC

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CCCCCCCCCCC