Weekend GI physio brain teasers -

[ArchivalUser]

Rav

1)Alcoholic male complaining of recurrent bouts of epigastric pain and loose,frothy stools develops paresthesias of hands and feet,loss of vibration and position sense and progressive spastic and ataxic weakness. Can you explain the underlying mechanism behind these clinical features?
Please answer with explanations

2)Patients may experience nausea and a sense of early satiety following
a) Surgical resection of proximal small bowel
b)Vagotomy of distal stomach
c)Surgical resection of proximal stomach
d)Surgical resection of antrum
e)Vagotomy of the proximal(orad) stomach

3)The absorption of which of the following sugars will be least affected if there is a decrease in ATP synthesis in the body
a)Glucose
b)Galactose
c)Fructose
d)Sucrose
e)Lactose

4)The triad of clinical features--hypersecretion of gastric acid,hypocalcemia and microcytic anemia is seen in inflammation of
a)Colon
b)Jejunum
c)Duodenum
d)Gallbladder
e)stomach

5)Atropine will be less effective in blocking which two events occuring in the G.I.T. caused by parasympathetic stimulation??


6)Patient given erythromycin for a repiratory tract infection develops diarrhea.The probable underlying mechanism is
a)loss of normal flora of the gut
b)drug acts on motilin receptors
c) a metabolite of the drug is not absorbed causing osmotic diarrhea
d)drug activates the cAMP pathway

7)What will be the best dietary advice regarding fat intake in a patient of malabsorption?
a)mainly unsaturated fatty acids
b)mainly long chain fatty acids
c)mainly medium chain fatty acids

[ArchivalUser]

Rav

Come on fellows--is no one ready to take up the challenge-???????????

[ArchivalUser]

student in miami

Ill do it tomorrow when I have more time....
Good luck
PD: by the way...great questions!

[ArchivalUser]

ali

1-dry beriberi with cerebellar manifestation and involvement of dorsal column

2-D

3-A

4- C

5-Parietal cells and gastric motility

6-A

7-C

[ArchivalUser]

mash

1 alcoholic--->pancreatitis(epigastric pain)----> decreased panc cleavage enz(to cleave off R factor)----->vit B12def--->neurological symptoms
panc enz def---->malabsorption---->lose frothy stools
3 sucrose
4 duodenum
6 a
7 c

[ArchivalUser]

mash

rav, wat r the answers ?

[ArchivalUser]

Rav

I will wait for a few more people to reply

[ArchivalUser]

USMLE_GIRL

1) Vitamin B-12 deficiency
2) D
3) D
4) C
5) ??
6) A
7) C

[ArchivalUser]

cheerkut

1... alcoholic pancreatitis.....decreases cleavage of R factor
hence B12 deficiency

2 D antral resection......early satiety...because of decreased stomach capacity.

3... fructose .....facilitated diffusion Glut5 luminal and glut2 on abluminal side
glucose/galactose is secondary active transport.requiring
maintenance of Na gradient.
4 Duodenitis....
5 LES tone is least affected by atropine ...VIP is the parasympathetic neurotransmitter
don,t know other exceptions.
6 Erythromycin acts on motilin receptors.
7 medium chain fatty acids

[ArchivalUser]

Rav

greeeeat work cheerkut---you got all right.The answer to q5--the other exception is release of gastrin by GRP.Fantastic work!!!!!