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Q.........Pharma... 2 - psychmledr
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02-09-2011, 08:18 PM
A 62-year-old man with a history of type 2 diabetes mellitus and ischaemic heart disease presents to his physician with erectile dysfunction. Which one of the following medications would contraindicate the prescription of sildenafil?
A. Metformin B. Isosorbide mononitrate C. Gliclazide D. Atorvastatin E. Clopidogrel
02-10-2011, 01:23 AM
its b,if u giv it,both are vasodilators which lead to profound hypotension
02-13-2011, 06:12 PM
Hello Dr Psychmledr,
Hope you are doing really well. Could you please post correct answer? I agree with option b as the other doctors said, but my confidence is really low and always want to check with the right answer. Thanks a lot and good luck with your studies.
02-13-2011, 06:33 PM
Hi Elpida
 Yes, the answer is B. Patients taking nitrates cannot take sildenafil concurrently as this may potentiate the vasodilating effects of such drugs. All the best to you too
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