03-06-2011, 01:54 AM
A 43-year-old woman presents with fatigue, a
4.5-kg (9.9-lb) weight gain over the past
3 months, cold intolerance, hair loss, and concentration problems. Physical examination is
signifi cant for dry, coarse skin and bradycardia.
She states that she had some slight swelling of
her lower neck several months ago, which resolved
without treatment. Results of antithyroglobulin
antibody and antinuclear antibody
tests are negative, but a thyroid peroxidase antibody
test is positive. What other autoimmune
diseases will this patient most likely have?
(A) Graves’ disease and pernicious anemia
(B) Osteoarthritis and Addison’s disease
© Rheumatoid arthritis and vitiligo
(D) Type 1 diabetes mellitus and celiac disease
(E) Whipple's disease and type 1 diabetes mellitus
4.5-kg (9.9-lb) weight gain over the past
3 months, cold intolerance, hair loss, and concentration problems. Physical examination is
signifi cant for dry, coarse skin and bradycardia.
She states that she had some slight swelling of
her lower neck several months ago, which resolved
without treatment. Results of antithyroglobulin
antibody and antinuclear antibody
tests are negative, but a thyroid peroxidase antibody
test is positive. What other autoimmune
diseases will this patient most likely have?
(A) Graves’ disease and pernicious anemia
(B) Osteoarthritis and Addison’s disease
© Rheumatoid arthritis and vitiligo
(D) Type 1 diabetes mellitus and celiac disease
(E) Whipple's disease and type 1 diabetes mellitus