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[ArchivalUser]

In an experiment, a series of immunohistochemical stains are employed to identify different cellular components. One particular stain identifies the presence of intermediate filaments within cells. This cytokeratin stain is most likely to be useful for which of the following diagnostic purposes?
A Cytoskeletal alterations indicate impending cell death
B A neoplasm is determined to be a carcinoma
C Contractile properties of the cells can be assessed
D A history of chronic alcoholism can be confirmed
E The degree of metaplasia or dysplasia can be assessed



A 38-year-old man incurs a traumatic blow to his upper left arm. He continues to have pain and tenderness even after 3 months have passed. A plain film radiograph reveals a 4 cm circumscribed mass in the soft tissue adjacent to the humerus. The mass contains areas of brightness on the x-ray. Over the next year this process gradually resolves. Which of the following terms best describes this process?
A Dysplasia
B Hyperplasia
C Hypertrophy
D Metaplasia
E Neoplasia

[ArchivalUser]

An experiment is conducted to determine if cell membrane injury is lessened by the effects of vitamin E ingestion. Which of the following cellular components is primarily involved in generation of lipid peroxides, the formation of which is inhibited by the vitamin E?

A Glutathione

B Ionized calcium

C Lactate

D Ferric iron

E Lipase

[ArchivalUser]

Ans: B,D.

[ArchivalUser]

Pls explain the answers Nilakash or Medico 25

[ArchivalUser]

for B) the brightness on x-ray suggests calcification from osseous metaplasia that developed in the healing process. This condition is known as myositis ossificans, because there is bone formation in the injured muscle.

[ArchivalUser]

(B)Carcinomas are derived from epithelium and contain cytokeratins, while sarcomas derived from mesenchymal cells contain vimentin.

(D)The brightness on x-ray suggests calcification from osseous metaplasia of connective tissues that developed in the healing process. This condition is known as myositis ossificans, because there is bone formation in the injured muscle.

(D) Ferric ion is needed for reduced oxygen species to injure cells. Hydroxyl radicals initiate lipid peroxidation.