NBME 3, block 2 - lovetest

[ArchivalUser]

During the conversion of proinsulin to insulin, bonds between which of the following amino acids residues keep the two chains of the insulin molecule together?
A. cysteine
B. Lysine
C. Methionine
D. Serine
E. Tyrosine

[ArchivalUser]

lovetest , pls help me with me nbme1,2,3,4,5,6,11and 12. my email is chinex791. thanks in advance.

[ArchivalUser]

Hi lovetest

A..

[ArchivalUser]

thank you, Maryam. I was just confused with FA picture of proinsulin molecule, I thought that two S's were standing for serine residues, but it was disulfide bonds.

@donpass, I'll try to send them to you now.

[ArchivalUser]

take a look at

http://www.google.com/imgres?q=proinsuli...66&bih=612

[ArchivalUser]

thank you Maryam, you are awesome. Also I have another questio from NBME3 block2.
A 69-y.o. man has been taking a dopamine agonist for 4 weeks for Parkinson dz. He has had some improvements from this treatment and decides on his own to increase the dosage. Which of the following adverse effects is most likely to result from this increase in dosage?
A. Depression
B. Exaggerated tremor
C. Generalized hypotonia
D. Psychosis
E. Tardive dyskinesia.

[ArchivalUser]

@donpass, do you have a skype ID??? the files are too big to send them via email.

[ArchivalUser]

DD

[ArchivalUser]

yp excess dopa=psychosis

[ArchivalUser]

thank you, ashlin. I answered psychosis as well, but I have read it can cause Tardive dyskinesia.