11-15-2011, 10:14 AM
A 9-month-old baby is brought to her pediatrician because she has suffered recurrent respiratory tract infections. At birth, she had coarse facial features and musculoskeletal deformities. Microscopic examination of her cells reveals large inclusion bodies due to the accumulation of undegraded products in lysosomes. An enzyme deficiency in which organelle is responsible for her disease?
A. Endoplasmic reticulum
B. Golgi apparatus
C. Mitochondria
D. Nucleus
E. Peroxisome