Patho3...Q - maryam2009

[ArchivalUser]

Three days following a viral illness, a 3-year-old child develops
severe vomiting and irritability, followed by lethargy. The concerned
parents take the child to the emergency room. Physical examination is
remarkable for hepatomegaly. The child is admitted to the hospital,
but over the next 24 hours, coma develops, and there is a marked
elevation in serum ammonia levels. Electron microscopy of brain or
liver would most likely reveal profound alterations in which of
the following cellular organelles?
A. Centromeres
B. Cilia
C. Mitochondria
D. Peroxisomes
E. Ribosomes

[ArchivalUser]

cc?

[ArchivalUser]

mitochondria ...C... is correct

[ArchivalUser]

C

[ArchivalUser]

The correct answer is C.

The child has Reye's syndrome (fatty liver with encephalopathy), which is an acquired mitochondrial abnormality (mechanism unknown) that can follow viral infections in children under 15 years of age. The cause is unknown, and although aspirin use has since been implicated, the syndrome may occur without exposure to salicylates. Reye's syndrome usually follows an upper respiratory tract infection, especially influenza or chickenpox. The mortality rate is near 50%, but if the child survives, full recovery is possible.

[ArchivalUser]

HI maryam GOd bless for ur question,u konw that u are the T helper cell of this forum. GL

[ArchivalUser]

..... You are very welcome