01-02-2012, 09:13 PM
Sickle chest syndrome is characterized by hypoxia, pulmonary infiltrates on chest radiograph, pain, and dyspnea in a patient with a sickling disorder. Acute chest syndrome may be caused by infection, in situ thrombosis, fat emboli, or a combination of these events. Management of patients with acute chest syndrome includes exchange transfusion to decrease the percentage of hemoglobin S. In addition, antibiotics, supplemental oxygen, and intravenous hydration may be necessary as clinically indicated. Incentive spirometry may be useful in patients with sickle cell crisis to prevent the sickle chest syndrome
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