Neuro...6-1 - maryam2009

[ArchivalUser]

Thalamic lesions are used to alleviate Parkinson's disease in cases that are refractory to L-dopa. What thalamic nucleus is the stereotaxic target for the neurosurgeons?


A. Centromedian.
B. Ventral posterior.
C. Lateral dorsal.
D. Ventral lateral.
E. Pulvinar.

[ArchivalUser]

DD

[ArchivalUser]

D

[ArchivalUser]

B ?????????

[ArchivalUser]

it is targeting subthalamic nucleus according to this source, no thalamus
http://www.sciencedirect.com/science/art...3097004498

[ArchivalUser]

the correct answer is D

Ventral lateral nucleus and ventral anterior nucleus project to premotor and supplementary motor regions which in turn project to precentral gyrus.
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A.Centromedian receives pallidal efferents, and its efferent connections are to the striatum. Therefore, if you want to affect the corticospinal tract this is not the best target.

B.Ventral posterior thalamus is the source of the somatosensory radiations to postcentral gyrus

C.Lateral dorsal is an association nucleus with connections to association cortex, not motor, premotor or supplementary motor cortex.

E.Pulvinar is an association nucleus with connections to temporal, occipital and parietal association cortical areas.
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Thank you