Pharm question - jdmed84

[ArchivalUser]

A 54-year-old woman with long-standing type 2 diabetes suffers from peripheral neuropathy and delayed gastric emptying. After many months of treatment for these symptoms, she begins to develop strange, involuntary repetitive movements in her face that do not cease when she stops her medication.


Which is the mechanism of action of the medication she most likely takes?
A. decreases lower esophageal sphincter tone
b. decreases transit time via colon
c. increases resting tone
d. increases transit time through the colon
e. increases upper esophageal sphincter tone


usmle RX..

[ArchivalUser]

Good question, definitely take a shot at it.

[ArchivalUser]

C ?

[ArchivalUser]

It is Metoclopramide which has D2 antagonistic effect on CTZ and causes acute dystonias ... also increases the lower esophageal sphincter tone

[ArchivalUser]

ans c metoclopramide.

[ArchivalUser]

good stuff

[ArchivalUser]

c is the ans

[ArchivalUser]

Drugs known for seizure side effect

1. metoclopramide
2. bupropion
3. tramadol
4. enflurane "e"= epilepsy
5. Evening primrose oil

-DIT...

[ArchivalUser]

why cant the ans be B ....
because in the question c option has not been mentioned for lower esophageal sphincter tone ...... its only resting tone
metoclopramide is both anti emetic and gastro pro kinetic .... accelerates transit through the gastrointestinal system , which itself may also contribute to the antiemetic effect......