Q-5/ Pathophysiology - saton

[ArchivalUser]

Which one disease is the single most common indication for single lung transplantation?


A. Chronic obstructive pulmonary disease (COPD) either smoking induced or secondary to alpha-1-antitrypsin deficiency
B. Cystic fibrosis
C. Lung cancer
D. Idiopathic pulmonary fibrosis (IPF)
E. Primary pulmonary hypertension (PPH)

[ArchivalUser]

It's weird, just the other day I had a patient with one lung removed because of the cancer! Clinical expirience really is valuable!

All the other mentioned diseases necessarily affect both lungs.

[ArchivalUser]

A. Chronic obstructive pulmonary disease (COPD) either smoking induced or secondary to alpha-1-antitrypsin deficiency

Yes, those diseases involve both lungs need lung transplantation most. I will pick A as the most common cause. Waiting for the correct answer.

[ArchivalUser]

C C C

[ArchivalUser]

Hey fox, the q is: Which one disease is the single most common indication for SINGLE lung (only one lung not both) transplantation?

Cheers!

[ArchivalUser]

Yes, lung cancer involves only one lung, maybe the other lung is functioning well and the patient will survive, so doesn't need a transplantation. That's what I am thinking.

[ArchivalUser]

Marq, I am not sure about my answer. I don't have clinical experience so very likely I will be wrong. Thank you for your reply.

[ArchivalUser]

Nice thinking fox maybe you're right. I just thought that all the other reasons mess up both of the lungs equaly enough to remove them both and only cancer can make big damage separately to only one of them.

[ArchivalUser]

Correct answer is A,

marq I think that you confuse what the Q stem was asking for. Lung cancer is not the "most common" indication for lung cancer transplantation.
I suggest you to look up these links.

http://www.lungusa.org/site/pp.asp?c=dvLUK9O0E&b=23012

http://www.csmc.edu/6992.html

http://www.ncbi.nlm.nih.gov/entrez/query...t=Abstract





Here is the explanation given

COPD accounts for about 60% of all single lung transplants and about 30% of bilateral lung transplant.

Cystic fibrosis accounts for approximately 36% of bilateral lung transplants and rests are miscellaneous reasons for lung transplant including idiopathic pulmonary fibrosis, primary pulmonary hypertension, and several other rarer lung diseases.

Cancer in the lungs or outside the lungs would preclude patients from undergoing lung transplantation.

[ArchivalUser]

Sorry folks "Lung cancer is not the "most common" indication for lung cancer transplantation. "

Sintax error. It should be: Lung cancer is not the most common indication for lung transplantation.