01-12-2014, 08:24 PM
A 26-year-old man with HIV and a history of
intravenous drug use presents to the emergency
department with 5 days of low-grade fever,
nonproductive cough, and dyspnea on exertion
that progressed to dyspnea at rest. His
oxygen saturation is 88% on room air. Arterial
blood gas analysis shows an arterial-alveolar
gradient of 45 and arterial oxygen pressure of
65 mm Hg. X-ray of the chest reveals diffuse
bilateral infi ltrates. Which of the following is
the most appropriate treatment?
(A) Ampicillin + gentamicin
(B) Intravenous clindamycin
© Isoniazid + pyrazinamide + rifampin +
ethambutol
(D) Third-generation cephalosporin +
doxycycline
(E) Trimethoprim-sulfamethoxazole +
oral prednisone
(F) Dapsone+doxycycline
(G) IV Atrovaquone
intravenous drug use presents to the emergency
department with 5 days of low-grade fever,
nonproductive cough, and dyspnea on exertion
that progressed to dyspnea at rest. His
oxygen saturation is 88% on room air. Arterial
blood gas analysis shows an arterial-alveolar
gradient of 45 and arterial oxygen pressure of
65 mm Hg. X-ray of the chest reveals diffuse
bilateral infi ltrates. Which of the following is
the most appropriate treatment?
(A) Ampicillin + gentamicin
(B) Intravenous clindamycin
© Isoniazid + pyrazinamide + rifampin +
ethambutol
(D) Third-generation cephalosporin +
doxycycline
(E) Trimethoprim-sulfamethoxazole +
oral prednisone
(F) Dapsone+doxycycline
(G) IV Atrovaquone