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nbme 15 qqqq - amira018
#1
A 2-month-old male infant is brought to the emergency department by his mother because of a 2-day history of generalized tonic-clonic seizures, myoclonus, and hiccuping. His mother says he has fed poorly and has been floppy since birth. Physical examination shows decreased deep tendon reflexes and hypotonia. A signaling defect in an inhibitory neurotransmitter is suspected. Which of the following neurotransmitter receptors most likely contains the defect?


Acetylcholine receptor
Aspartic acid receptor
Epinephrine receptor
Glutamate receptor
Glycine receptor

whats is the diagnosis and what is the answer????
someone plzzz help
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#2
glycine receptors..tetanus..
probably the mother did not take tetanus vaccination while pregnant..hence the baby got it
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#3
Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccine. One dose of Tdap vaccine is recommended during each pregnancy to offer protection from whooping cough (pertussis), tetanus and diphtheria, regardless of when you had your last Tdap or tetanus-diphtheria (Td) vaccination. Ideally, the vaccine should be given between 27 and 36 weeks of pregnancy. Whooping cough can be dangerous — even life-threatening — for infants. Getting the Tdap vaccine during pregnancy can help protect you from the infection and might also help protect your baby after birth.
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#4
thanks for ur reply atkal
but does tetanus cause seizures????
this kind off questions make me so dishearted :-(
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#5
GABA and glycine are inhibitory neurotransmitters, release of these two is inhibited in tetanus.
But is the diagnosis here "tetanus" or "Botulism" ? Cz tetanus causes spastic paralysis, not hypotonia
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