@acestep, before u thank me lets make sure u understand it and my ATPs not wasted here
A 49 y/ o visited you and complaining of fatigue, low libido, and moderate generalized joint pains of approximately 1yr duration. The joint pains were mostly in the fingers, wrists, hips, knees, and ankles. His parents, both dead, were born in Scotland but emigrated to Canada in early adulthood. The patient had no siblings and did not smoke or drink. He occasionally took acetaminophen for his joint pains, but otherwise was not receiving any medication. An uncle had died of liver cancer about 10 years previously. In addition to stiffness and slight swelling over some joints, the physician noted grayish skin pigmentation, most prominent in exposed parts, and for that reason referred the patients to an internist, who also noted that the liver edge was firm and palpable just below the costal margin. The internist suspected hereditary hemochromatosis and ordered appropriate laboratory tests as well as x-rays of the hands, hips, knees, and ankles. X-rays of the joints showed loss of articular cartilage, narrowing of joint spaces, and diffuse demineralization. You do liver bipsy and histo exam revealed moderate periportal fibrosis amd aggregates of ferritin micelles was visible as golden brown granules in both parenchymal and bile duct epithelial cells noted.
Lab
Normal reference values in parentheses bz i want be nice to u i provide that as gift ( but in real exam u have to click on it to get this value and that take time
Hb, 120 g/L (133–162 g/L, males)
RBC, 4.6 × 10*12/L (4.30–5.60 × 10*12/L, males)
Glucose (fasting), 5 mmol/L (4.2–6.1 mmol/L)
Alanine aminotransferase [ALT], 1.8 μkat/L or 105 units/L (0.12–0.70 μkat/L or 7–41 units/L)
Plasma iron, 50 μmol/L (7–25 μmol/L)
Total iron-binding capacity, 55 μmol/L (45–73 μmol/L)
Transferrin saturation with iron 82% (16–35%)
Q1)Whats dx?
Q2)What in lab value most important part made u to dx it?
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