nbme 15 q? - alekyamanasa03

[ArchivalUser]

difference in pathway of ikb of nfkb from il 1 to IL 6?

a attaches to cytokine receptor
b facilitates cleavage of nfkb
c phosphorylates nfkb
d releases nfkb after phosphoryltaion
e translocation to nucleus after undergoing phosphorylation

[ArchivalUser]

answer?

[ArchivalUser]

DDD
http://www.youtube.com/watch?v=iVMIZy-Y3...re=related

[ArchivalUser]

http://www.usmleforum.com/showthread.php?tid=715697

[ArchivalUser]

ddd

[ArchivalUser]

ikk phosphorylates ikb-nfkb complex n releases nfkb n this nfkb translocates to the nucleus to bind to response elements. ikb is inhibitory to nfkb. nkfb is present in the cytoplasm.
so first option D will take place then option E will take place.

[ArchivalUser]

but it seems there is difference in the pathway for IL 1 to IL 6,
wHAT IS IT?