07-24-2014, 01:55 AM
1) 30 yr women with Lfraumeni syndrome is found to have adenocarcinoma of breast.Her family history includes osteosarcoma.which of following mechanisms most likely underlies this condition?
A)activated protooncogenes
B)defective detoxification enzymes
C)defective DNA repair enzymes
D)impaired regulation of apoptosis
E)impaired signal transduction
2) poliovirus mRNA lacks 5`m7 G cap but is translated efficiently by cellular ribosomes.which of the following additional findings of poliovirus mRNA is most likely cause of its ability to be translated in absence of a cap?
A)absence of 3` UTR
B)absence of 5`UTR
C)absence of poly tail
D)presence of an internal ribosome entry site
E) very short open reading frame
A)activated protooncogenes
B)defective detoxification enzymes
C)defective DNA repair enzymes
D)impaired regulation of apoptosis
E)impaired signal transduction
2) poliovirus mRNA lacks 5`m7 G cap but is translated efficiently by cellular ribosomes.which of the following additional findings of poliovirus mRNA is most likely cause of its ability to be translated in absence of a cap?
A)absence of 3` UTR
B)absence of 5`UTR
C)absence of poly tail
D)presence of an internal ribosome entry site
E) very short open reading frame