@ FA doubt,, how CA inh causes proximal renal - examb4

[ArchivalUser]

tubular ACIDOSIS? not alkolosis? since HCO3 not been reabsorbed?

[ArchivalUser]

Well CA inhibitor causes u to lose HCO3 making yur URINE basic and you BlOOD acidic INITIALLY!!! thats right

This can cause a type 2 renal tubular acidosis.....

When taking abt RTA we are referring to the blood not the urine.....so u lose HCO3 yur blood becomes ACIDIC...cool

But the thing about losing HCO3 is that INITIALLY u have an alkalotic urine but with time when u are depleated of HCO3 yur urine becomes ACIDIC!!!! Coz u dnt have HCO3 but can still excrete H+.

So u see an acidic blood with acidic urine in case of type 2 DTA

[ArchivalUser]

THANKS you littleturtle!!

[ArchivalUser]

My pleasure examb4