08-01-2016, 07:07 PM
A 3 year old girl is brought to the physician because of fever and rapid breathing for 1 day. She has had episodes of otitis media and sinusitis since the age of 1 year. Her temperature is 39C (102F), and respirations are 24/min. she is at the 10th percentile for height and weight. Physical examination shows tachypnea. Crackles and rhonchi are heard in all lung fields. Heart tones are heard best on the right side of the chest. A chest x-ray shows bilateral infiltrates, dextrocardia and stomach bubble on the right. A deficiency of which of the following is the most likely cause of this patient’s disorder?
a. Adenosine deaminase activity
b. Bruton tyrosine kinase activity
c. Cystic fibrosis transmembrane regulator
d. Dynein
e. Fibrillin-1
a. Adenosine deaminase activity
b. Bruton tyrosine kinase activity
c. Cystic fibrosis transmembrane regulator
d. Dynein
e. Fibrillin-1