Drug 1 - shinenrise

[ArchivalUser]

A 56-year-old Caucasian male with non-Hodgkin lymphoma is undergoing systemic chemotherapy. Vincristine is a part of the regimen, and you suspect accidental overdose of that agent Which of the foUowing would you most expect in this patient?

A. Finger numbness and tingling
B. Burning on urination and urgency
C. Leg swelling and orthopnea
D. Dry cough and exertional dyspnea
E. Tarrylstool and fatigue
F. Abdominal pain and jaundice

[ArchivalUser]

A vincristine cause peripheral neuropathy

[ArchivalUser]

A.

[ArchivalUser]

Correct!
its A- vincristin- m-phase drug , its toxicity interferes with microtubule formation in nerve axons,leading to peripheral neuropathy.Neurotoxicity is dose limiting effect.