06-03-2006, 11:02 AM
Can anyone explain the following "Cushing" terms?
Cushing's syndrome
Cushing's disease
Cushing's Triad
Cushing's reflex?
Cushing's syndrome
Cushing's disease
Cushing's Triad
Cushing's reflex?
All about Cushing's! - malvika
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06-03-2006, 11:02 AM
Can anyone explain the following "Cushing" terms?
Cushing's syndrome Cushing's disease Cushing's Triad Cushing's reflex?
06-03-2006, 11:36 AM
Cushing's syndrome- Hypercortisolism ie glococorticoid excess from any cause including cushing's disease.
Cushing's disease- pituitary cause glucocoticoid excess. Cushing's Triad- due to raised ICT- 1. Hypertension. 2. Bradycardia. 3. abnormal respirations Cushing's reflex- increased BP, decreased heart rate. A hypothalmic response to ischaemia, usually due to poor perfusion to the brain. Ischaemia ----> activates sympathetic nervous system--->increase in the heart's output + peripheral constriction of the blood vessels---->causes rise in blood pressure, ensuring blood delivery to the brain. The increased blood pressure---->stimulates the baroreceptors-----> activation of the parasympathetic nervous system, which slows down the heart rate, causing the bradycardia
06-03-2006, 11:46 AM
Excellant,Destiny's choice! Very detailed and informative--thank you soo much!
06-03-2006, 11:47 AM
hope it helps
It was a favourite question in my MRCS exams - cushing reflex and i have personally seen such a case pt came with head injury GCS 4-5/ 15, pupils fixed, checked his BP it was 170 / 100 mmof Hg. was expecting tachycardia but the heart rate was 40 - 50 b/ sec , that was when my consultant told me about cushing reflex... any way the pt died my consultant also told that once U see the cushing triad that means the pt will cone any time... and that happened. ideally they do a decompression crainotomy... so i can never forget cushing reflex...
06-03-2006, 12:06 PM
and dont forget about cushings ulcer, a stress ulcer!
06-03-2006, 12:09 PM
Thats so interesting, destiny--really experience is the best teacher! Hey, thanks docspring ,for another forgotten Cushing's association!
06-03-2006, 12:14 PM
You are welcome.
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