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lg - explanation
#1
21. A middle-aged pt with acute diverticulitis develops severe hypotension, tachypnea and tachycardia subsequently develops cyanosis and hypoxemia unresponsive to oxygen therapy. X-ray films of the chest show a diffuse alveolar infiltrate. Blood culture grows E. coli. A major factor in the pathogenesis of this syndrome is
1. degranulation of mast cells
2. delaysed (type 4) hypersensitivity to bacterial products
3. increased surfactant production by type 2 pneumocytes
4. production of antibodies ot alveolar basement membraned
5. release of oxygen free radicals from sequestered neutrophils

22. Methimazole is effective for the treatment of Graves™ disease because it inhibits thyroidal peroxidase activity! True or false

23. A 60 yrs pt receives a sintered tintanium oxide implant during hip arthroplasty following traumatic injury. During the first 6 weeks following surgery, bone ingrowth anneals to the bonemetal interface in both the femur and acetabulum, thus securing the prosthesis in position. Type 1 collagen secretion in the first stage of matrix formation is mediated by which of the following cell types?
1. Chondrocytes
2. Chondroblasts
3. Endothelial cells
4. Osteoblasts
5. Osteocytes
6. Macrophages
7. Osteoclasts

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#2
21) 4 ???

22) true

23) Endothelial cells i think
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#3
23) 4
21)2 or 5
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#4
5 True and 4
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#5
21 5) endotoxic shock.... sepsis due to E coli has to be neutrohil mediated injury
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#6
21. 5
22. True
23.4
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#7
21.......2 ??
22......true
23......2
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#8
22......true
23.....osteoblasts is the correct answer. they lay down the type 1 collagen and which later gets mineralised.
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