07-05-2006, 04:32 PM
Which one of the following statements concerning the effects of diuretics on the kidney is correct?
A: Diuretics that affect the proximal tubule are the most efficacious class of diuretics because the majority of reabsorption occurs in the proximal tubules
B: Loop diuretics may cause kidney stone formation because of the reduction of the electrical potential that normally enhances the reabsorption of calcium
C: Thiazide-type diuretics, which act in the distal tubule, can cause metabolic acidosis
D: Because only approximately 20% of sodium reabsorption occurs in the loop of Henle, loop diuretics are suitable only for cases of very mild edema
E: Aldosterone antagonists act mainly in the proximal tubule
F: Osmotic diuretics are frequently useful as oral agents in patients with severe edema
A: Diuretics that affect the proximal tubule are the most efficacious class of diuretics because the majority of reabsorption occurs in the proximal tubules
B: Loop diuretics may cause kidney stone formation because of the reduction of the electrical potential that normally enhances the reabsorption of calcium
C: Thiazide-type diuretics, which act in the distal tubule, can cause metabolic acidosis
D: Because only approximately 20% of sodium reabsorption occurs in the loop of Henle, loop diuretics are suitable only for cases of very mild edema
E: Aldosterone antagonists act mainly in the proximal tubule
F: Osmotic diuretics are frequently useful as oral agents in patients with severe edema