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+--- Thread: Drug of choice for: - harry206 (/showthread.php?tid=477111)
Drug of choice for: - harry206 - ArchivalUser - 01-14-2010
Pt with ADHD and family h/o tic disorder
...............
0 - ArchivalUser - 01-14-2010
Desipramine.
0 - ArchivalUser - 01-14-2010
Central alpha agonists
Central alpha agonists can be helpful in treating hyperactivity, tics, or delayed sleep onset. They have a long history of pediatric use for this indication. Rare cases of sudden death had been reported several years ago in a few children who were given clonidine with concurrent methylphenidate
1.Guanfacine (Intuniv)
Selectively stimulates alpha2a-adrenoreceptors in brainstem, activating an inhibitory neuron, which reduces sympathetic outflow.
2.Clonidine (Catapres)
Stimulates alpha2-adrenoreceptors in brainstem, activating an inhibitory neuron, which reduces sympathetic outflow. Result is decreased vasomotor tone and HR.
0 - ArchivalUser - 01-14-2010
Ans: desipramine.