Drug of choice for: - harry206

[ArchivalUser]

Pt with ADHD and family h/o tic disorder

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[ArchivalUser]

Desipramine.

[ArchivalUser]

Central alpha agonists
Central alpha agonists can be helpful in treating hyperactivity, tics, or delayed sleep onset. They have a long history of pediatric use for this indication. Rare cases of sudden death had been reported several years ago in a few children who were given clonidine with concurrent methylphenidate
1.Guanfacine (Intuniv)
Selectively stimulates alpha2a-adrenoreceptors in brainstem, activating an inhibitory neuron, which reduces sympathetic outflow.
2.Clonidine (Catapres)
Stimulates alpha2-adrenoreceptors in brainstem, activating an inhibitory neuron, which reduces sympathetic outflow. Result is decreased vasomotor tone and HR.

[ArchivalUser]

Ans: desipramine.