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+--- Thread: Hyperaldosteronism and Liver Cirrhosis - habiballah (/showthread.php?tid=625148)
Hyperaldosteronism and Liver Cirrhosis - habiballah - ArchivalUser - 10-25-2011
Hi guys, I know it's somehow realted to the RAA axis being more activated, can anyone explain the mechanism more (how hyperaldos can happen due to cirrhosis).
Thanks
0 - ArchivalUser - 10-25-2011
You are right. It is related to RAA system. Please look at this link. It will help you understand.
http://en.wikipedia.org/wiki/Hepatorenal_syndrome
0 - ArchivalUser - 10-25-2011
drop albumin--- plasma leaks to interstitial space--- hypovolemic---drop GFR---activation of beta1 receptor by symp activity, and inc of renin release by reduced sodium in DCT
both---RAAS activation