Hyperaldosteronism and Liver Cirrhosis - habiballah

[ArchivalUser]

Hi guys, I know it's somehow realted to the RAA axis being more activated, can anyone explain the mechanism more (how hyperaldos can happen due to cirrhosis).
Thanks

[ArchivalUser]

You are right. It is related to RAA system. Please look at this link. It will help you understand.

http://en.wikipedia.org/wiki/Hepatorenal_syndrome

[ArchivalUser]

drop albumin--- plasma leaks to interstitial space--- hypovolemic---drop GFR---activation of beta1 receptor by symp activity, and inc of renin release by reduced sodium in DCT

both---RAAS activation