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Ques - ira3 - ArchivalUser - 11-08-2015

149) A 29 year old internal medicine resident physician has been exposed to a patient with cavitary pulmonary tuberculosis 1 month ago. He denies any symptoms. His physical examination is normal. A tuberculin skin test reaction is positive now at 6mm. His Skin test one year ago was negative. A chest X-ray is within normal limits and chemistry panel is normal. The most appropriate management optiuon for this patient is :

A) Isoniazid, Pyrazinamide, Rifampin and Ethambutol for 9 months

B) Observation as ≥ 10mm is considered positive in health care workers

C) Isoniazid for 9 months

D) Rifampin for 9 months

E) Isoniazid for 6 months


0 - ArchivalUser - 11-08-2015

cc


0 - ArchivalUser - 11-08-2015

B. and repeat ppd in 3 months


0 - ArchivalUser - 11-08-2015

does cavitatory TB will be high risk? y not c?


0 - ArchivalUser - 11-09-2015

b



0 - ArchivalUser - 11-09-2015

if it is not C then WHY they did CXR on him, because if the answer is C then we need the CXR


0 - ArchivalUser - 11-09-2015

where are this questions from ?
can you please tell us.

thank you


0 - ArchivalUser - 11-09-2015

I go with B


0 - ArchivalUser - 11-10-2015

from archer


0 - ArchivalUser - 11-10-2015

It's not B because the cutoff is lower in health and prison workers.

After treatment they receive follow-up chest x-rays

If the patient gets any side-effects (i.e., vivid dreams) on Isoniazid (unrelated to B6 deficiency) you'd do LFTs, THEN switch them to Rifampin. This mans you remember to advise them about orange/red bodily fluids, and any meds they're taking metabolized through the cyp-P450 (especially OCPs), and monitoring liver enzymes. IIRC, LFTs rising to 5X their baseline is the cut-off for stopping Rifampin.

The orange/red bodily fluids is not a side effect. It's because the drug is suspended in something orange/red.

A harder question would be which drugs can't you give during pregnancy.