q_____________? - sarim

[ArchivalUser]

http://www.aids-info.ch/imagesv1/HIV/stadien_en.gif


In "Acute phase" of HIV infection, the viral load spikes and then declines (red graph).This decline in viral load is in response to the action of which type of cells ?

[ArchivalUser]

well that is CD8

[ArchivalUser]

yes cytotoxic CD8

[ArchivalUser]

yes CD8+ response is the most important factor to control initial viremia.

[ArchivalUser]

CD8+

[ArchivalUser]

correct.

it is CD8+ response against HIV infected cells that brings the initial rise in viral load down which is correlated with some increase in CD4+ count as u can see in the blue graph.

[ArchivalUser]

CD8+ cells control the initial viremia but cant eradicate it...also enhance effect of CD8+ is bcz of CD4+ cells...but then of course CD4+ cells are also them self infected...so CD8+ cells also kills CD4+ cells that decline the number of CD4+ cells....moving towards AIDS....