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A clinical study of hepatitis B infection is conducted. It is observed that when hepatocytes become infected by hepatitis B virus, macrophages that encounter this hepatocyte are activated. Which of the following substances elaborated by this macrophage is most likely to result in subsequent activation of NK cells?
A Interferon gamma
B Interleukin-12
C Nitric acid
D Phagocyte oxidase
E Tumor necrosis factor
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CORRECT. IL-12 is particularly helpful in stimulating NK cells to destroy the virally infected cell.
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ok ...how bout ..substance which ll inhibit NK CELL???
WHICH MOLECULE INHIBIT NK CELL???
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why cant it be A OR E which will stimulate nk cells, its given in kaplan immunolgy page 384, diagram representation, TH 1 --INF GAMMA----CD8, NKCELLS. CAN U GUYS CLARIFY MY DOUBT? WHY IS IT ONLY IL 12 STIMULATING NK?
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just look into NUTSHELL on page 382.
