nbme 16....please explain - ahmad12801

[ArchivalUser]

An animal study is conducted to assess the effects of smoking on pulmonary defense and maintenance mechanisms. For 1 week, normal
male rats are exposed to levels of cigarette smoke comparable to those encountered by humans who smoke cigarettes. Results of
pulmonary testing are compared with baseline levels obtained the week before the smoke exposure. Which of the following sets of changes
is most likely to be observed? Is everything low? smoking impairs mucocilliary clearance I know that much..

Mucus Production and Secretion up/down

Alveolar Macrophage Function up/down

Activity of Airway Cilia up/down

[ArchivalUser]

i think

1-up
2-up
3-up

i guess
activity of airway cilia is down for chronic smoker.here it is only 1wk.

[ArchivalUser]

i got it wrong

[ArchivalUser]

Up , up , down . I said down because smoking irritate and destroy cilia

[ArchivalUser]

Correction :

down , up , down . I had doubt that 1 week wouldn't affect the cilia but it wouldn't increase neither . if the option was " normal cilia " I would have pick normal cilia but not increase. Please let me know you feedback

[ArchivalUser]

Thanks for the question ahmad , after further reading I believe all are down.

http://www.ncbi.nlm.nih.gov/pubmed/2846725