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NBME 5 ans plz... - arpddvd4u
#1
A biosynthetic error in reading the genetic code gives rise to an enzyme that folds in an abnormal manner.Which of the following is most likely to happen to this enzyme?

a denaturation and refolding
b faster degradation
c inactivation by phosphorylation
d tansportation out of the cell via the golgi complex

A 66year old man who is undergoing chemotherapy for lekumia has a 3 day history of progressive fever,headache,nausea, and deteoration of mental acuity.analysis of csf shows lymphocytic pleocytosis,a normal glu conc. , and a slightly increased protein conc..The causual agent is presumptively identified by a positive Indian ink test and later confirmed with culture Which of the following is the major virulence factor of the infecting organism producing this disease?

a antigenic variation
b exotoxin
c Ig protease
d leuckocidin
e polysaccharide capsule
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#2
E.polysaccharide capsule ..
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#3
09usmle ,

acc to ques lymphocytic pleocytosis,a normal glu conc. , and a slightly increased protein conc.. goes in favour of viral or fungal etiology but not bacterial .. and =ve indian ink test,m thinking of cryptococcous ???

key says E. but im doubtful so could u explain why E???
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#4
Q1 B ( ubiquitin mediated degradation )

Q2- E
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#5
hi arpddvd4u,
you are thinking absolutely right .
this is cryptococus..that has thick poltsacharide capsule .
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