02-07-2007, 10:06 AM
8-36. The answer is a. (Hardman, p 338. Katzung, pp 438“439.) Ester-type
local anesthetics are mainly hydrolyzed by pseudocholinesterases. Amidetype
local anesthetics are hydrolyzed by microsomal enzymes in the liver. Of
the listed agents, only lidocaine is an amide and can be influenced by liver
dysfunction.
local anesthetics are mainly hydrolyzed by pseudocholinesterases. Amidetype
local anesthetics are hydrolyzed by microsomal enzymes in the liver. Of
the listed agents, only lidocaine is an amide and can be influenced by liver
dysfunction.