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how do we treat cold IgM hemolysis problem ( steroid-->splenectomy--> cyclophosphamide??)
and how we manage waldenstrom's hyperviscosity from high IgM (plasmapheresis?)
little confused pls put some input
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wald. is tx with plasmapheresis, and then u tx the underlying lymphoma.
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igm hemoly. is tx with steroids
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Mx of IgM hemolysis:
first avoid cold...............If fails, cyclosporine/cyclophosphamide/azathioprne
Can use Rituximab
steroid n splenectomy - as distruction is in liver..... never use in IgM ds
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not sure about waldenstrom's hyperviscosity Mx